Tunturi T, Leikkonen O, Paakkala T, Lepistö P, Rokkanen P
Arch Orthop Trauma Surg (1978). 1979 Jun 29;94(1):1-9. doi: 10.1007/BF00448086.
The aim of this study was to evaluate the long-term results of Cloward's anterior interbody fusion of the cervical spine and to identify the factors influencing them. The series consisted of 29 patients operated on in 1968--75. The indication for operation was in 12 cases intensive radicular symptoms, not responding to conservative treatment, in connection with considerable degeneration of the corresponding spinal segment only, and in 17 cases instability of the cervical spine caused by traumatic injury followed by dislocation and radicular or medullary symptoms enhancing in spite of conservative treatment by skull traction or collar. Twenty-five patients (86%) attended follow-up after an average time lapse of 6.5 years from operation. The operative result was evaluated considering objective neurological improvement, subjective improvement, present symptoms and working capacity. The operative result was at least fair in 7/11 in the degeneration group and in 12/14 in the traumatic injury group. All fusions were radiologically successful. Adequate correction of a primary flexion deformity of more than 15 degrees was not achieved. Age over 35 years and motor defect preoperatively proved to be statistically significant prognostic factors for a poor operative result in the traumatic injury group. Preoperative sick-leaves and a duration of preoperative symptoms exceeding six months proved to be prognostic factors for a poor result in the degeneration group. In spite of the relatively good clinical results obtained, this study does not justify any conclusions concerning the value of Cloward's procedure compared to other methods of treatment, since no control material was available.
本研究的目的是评估克劳德颈椎前路椎间融合术的长期效果,并确定影响这些效果的因素。该系列包括1968年至1975年接受手术的29例患者。手术指征为:12例患者有严重神经根症状,对保守治疗无反应,仅伴有相应脊柱节段的明显退变;17例患者因创伤性损伤导致颈椎不稳,继之出现脱位,尽管经颅骨牵引或颈托保守治疗,神经根或脊髓症状仍加重。25例患者(86%)在术后平均6.5年接受了随访。根据客观神经功能改善、主观改善、目前症状和工作能力对手术结果进行评估。退变组11例中有7例、创伤损伤组14例中有12例手术结果至少为尚可。所有融合在影像学上均获成功。未能充分矫正超过15度的原发屈曲畸形。术前年龄超过35岁和运动功能缺陷在创伤损伤组被证明是手术结果不佳的统计学显著预后因素。术前病假和术前症状持续时间超过6个月在退变组被证明是预后不良的因素。尽管取得了相对较好的临床结果,但由于没有对照材料,本研究无法就克劳德手术与其他治疗方法相比的价值得出任何结论。