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Effects of 1,3-bis(2-chloroethyl)-1-nitrosourea and related compounds on nuclear RNA metabolism.

作者信息

Kann H E, Kohn K W, Widerlite L, Gullion D

出版信息

Cancer Res. 1974 Aug;34(8):1982-8.

PMID:4858341
Abstract
摘要

相似文献

1
Effects of 1,3-bis(2-chloroethyl)-1-nitrosourea and related compounds on nuclear RNA metabolism.1,3-双（2-氯乙基）-1-亚硝基脲及相关化合物对核RNA代谢的影响
Cancer Res. 1974 Aug;34(8):1982-8.
2
A comparison of the effects of alkylating agents 1,3-bis(2-chloroethyl)-1-nitrosourea, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea and nitrogen mustard on nuclear RNA synthesis and processing.烷化剂1,3-双（2-氯乙基）-1-亚硝基脲、1-（2-氯乙基）-3-环己基-1-亚硝基脲和氮芥对核RNA合成与加工影响的比较。
Biochim Biophys Acta. 1974 May 31;349(3):389-401. doi: 10.1016/0005-2787(74)90125-7.
3
DNA damage and repair in mouse leukemia L1210 cells treated with nitrogen mustard, 1,3-bis(2-chloroethyl)-1-nitrosourea, and other nitrosoureas.用氮芥、1,3-双（2-氯乙基）-1-亚硝基脲及其他亚硝基脲处理的小鼠白血病L1210细胞中的DNA损伤与修复
Cancer Res. 1977 Jul;37(7 Pt 1):2114-22.
4
[Disruption of DNA synthesis and structure of mouse L1210 leukemia cells, sensitive and resistant to 1-methyl-1 nitrosourea and 1,3-bis(2-chloroethyl)-1-nitrosourea in vivo].[体内对1-甲基-1-亚硝基脲和1,3-双(2-氯乙基)-1-亚硝基脲敏感和耐药的小鼠L1210白血病细胞的DNA合成及结构破坏]
Biokhimiia. 1984 Jul;49(7):1189-98.
5
Effects of structure and chemical activity on the ability of nitrosoureas to inhibit DNA repair.结构和化学活性对亚硝基脲抑制DNA修复能力的影响。
Cancer Res. 1980 Jan;40(1):50-5.
6
The effect of 5-fluorouracil on the synthesis and methylation of low molecular weight nuclear RNA in L1210 cells.5-氟尿嘧啶对L1210细胞中低分子量核RNA合成及甲基化的影响。
Mol Pharmacol. 1980 Mar;17(2):245-9.
7
Growth support of small B16 melanoma implants with nitrosourea-sterilized fractions of the same tumor.用亚硝基脲灭菌的同一种肿瘤组分对小型B16黑色素瘤植入物的生长支持作用。
Cancer Res. 1976 Jun;36(6):2031-4.
8
The antitumor effects of anthracyclines. The importance of the carbomethoxy-group at position-10 of marcellomycin and rudolfomycin.
Mol Pharmacol. 1979 Mar;15(2):341-56.
9
Comparison of biochemical and biological effects of four nitrosoureas with differing carbamoylating activities.四种具有不同氨甲酰化活性的亚硝基脲的生化和生物学效应比较。
Cancer Res. 1978 Aug;38(8):2363-6.
10
[The role of N-nitrosourea-induced changes in the nucleoid structure and activity of repair enzymes in the development of drug resistance in mice with leukemia L1210].[N-亚硝基脲诱导的核仁结构变化及修复酶活性在白血病L1210小鼠耐药性发展中的作用]
Biokhimiia. 1987 Aug;52(8):1335-43.

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Renal toxicity and chemotherapy in children with cancer.癌症患儿的肾毒性与化疗
Br J Clin Pharmacol. 2017 Dec;83(12):2605-2614. doi: 10.1111/bcp.13388. Epub 2017 Sep 20.
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Novel drugs in pediatric gliomas.小儿胶质瘤的新型药物
Oncol Lett. 2017 May;13(5):2881-2885. doi: 10.3892/ol.2017.5812. Epub 2017 Mar 6.
3
What is the translational efficacy of chemotherapeutic drug research in neuro-oncology? A systematic review and meta-analysis of the efficacy of BCNU and CCNU in animal models of glioma.神经肿瘤学中化疗药物研究的转化疗效如何？对卡莫司汀（BCNU）和洛莫司汀（CCNU）在胶质瘤动物模型中的疗效进行系统评价和荟萃分析。
J Neurooncol. 2009 Jan;91(2):117-25. doi: 10.1007/s11060-008-9697-z. Epub 2008 Sep 24.
4
DNA crosslinking and cytotoxicity in normal and transformed human cells treated with antitumor nitrosoureas.用抗肿瘤亚硝基脲处理的正常和转化人细胞中的DNA交联与细胞毒性
Proc Natl Acad Sci U S A. 1980 Jan;77(1):467-71. doi: 10.1073/pnas.77.1.467.
5
Membrane and cytoplasmic changes in 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU)-sensitive and resistant human malignant glioma-derived cell lines.
J Neurooncol. 1983;1(3):237-48. doi: 10.1007/BF00165608.
6
Toxicity of inhaled methyl isocyanate in F344/N rats and B6C3F1 mice. I. Acute exposure and recovery studies.F344/N大鼠和B6C3F1小鼠吸入甲基异氰酸酯的毒性。I. 急性暴露和恢复研究。
Environ Health Perspect. 1987 Jun;72:53-61. doi: 10.1289/ehp.877253.
7
Experiments on the chemotheraphy of a transplantable glioblastoma in the rat, employing 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU).
Acta Neurochir (Wien). 1978;42(1-2):103-8. doi: 10.1007/BF01406636.