Young N P, Ash R J
Appl Microbiol. 1974 Jul;28(1):26-30. doi: 10.1128/am.28.1.26-30.1974.
The adsorption characteristics of Newcastle disease virus (NDV) propagated in chicken cells (NDV-C) and in human cells (NDV-H) were examined. Adsorption experiments performed at different temperatures indicated that virus propagated in a particular cell infected that cell type more readily than did virus propagated in a different host. For example, NDV-C was more efficient in initiating infection of chicken cells at 22 C than was NDV-H; the reverse was true when human cells were employed. The results indicate that infection of susceptible cells by NDV is influenced by the host cell in which the virus was propagated. The data also suggest that NDV may be useful in studies on homologous and heterologous membrane-membrane interactions.
对在鸡细胞(NDV-C)和人细胞(NDV-H)中增殖的新城疫病毒(NDV)的吸附特性进行了检测。在不同温度下进行的吸附实验表明,在特定细胞中增殖的病毒比在不同宿主中增殖的病毒更容易感染该细胞类型。例如,在22℃时,NDV-C比NDV-H更有效地引发鸡细胞感染;使用人细胞时情况则相反。结果表明,NDV对易感细胞的感染受病毒增殖所在宿主细胞的影响。数据还表明,NDV可能有助于同源和异源膜-膜相互作用的研究。