Rizzo P A, Amabile G, Caporali M, Pierelli F, Spadaro M, Zanasi M, Morocutti C
Biol Psychiatry. 1979 Aug;14(4):581-6.
The authors carried out a longitudinal study in five subjects with bipolar cyclothymic psychosis, recording contingent negative variations in the same patients in the different phases of illness and under normal clinical conditions. An average voltage decrease was found in the depressive phases and a more conspicuous decrease in the manic phases. Furthermore, an evident postimperative negative variation was present in four subjects during the manic phase. The authors set forth tentative psychological and neurophysiological interpretation of their results.
作者对5例双相环性心境障碍患者进行了一项纵向研究，记录了这些患者在疾病的不同阶段以及正常临床状态下的关联性负变。结果发现，抑郁期平均电压下降，躁狂期下降更为明显。此外，4例患者在躁狂期出现明显的指令后负变。作者对其研究结果提出了初步的心理学和神经生理学解释。
