冠心病中可能的有毒水质因素。

Possible toxic water factor in coronary heart-disease.

作者信息

Bierenbaum M L, Fleischman A I, Dunn J, Arnold J

出版信息

Lancet. 1975 May 3;1(7914):1008-10. doi: 10.1016/s0140-6736(75)91949-2.

DOI:10.1016/s0140-6736(75)91949-2

Abstract

Many reports indicate a significant negative correlation between death-rates for coronary heart-disease (C.H.D.) and water hardness. A reverse situation exists in the twin Kansas cities, U.S.A. Kansas City, Kansas, has water which is more than twice as hard as the softened water of Kansas City, Missouri, from the same source. Serum cholesterol and triglyceride levels were similar, but blood-pressure was higher in Kansas City, Kansas, and this correlated with higher serum-sodium, lower serum-potassium, and a tenfold higher serum-cadmium. Serum calcium and magnesium levels were higher in Kansas, while copper, chromium, cobalt, and zinc were higher in Missouri. The serum studies were con ducted on two matched groups of 260 adults from each of the sample cities. Hypertension may account for the reverse C.H.D. rate noted and be cadmium related.

摘要

许多报告表明，冠心病（C.H.D.）死亡率与水硬度之间存在显著的负相关。美国堪萨斯州的两个孪生城市情况相反。堪萨斯州的堪萨斯城的水硬度是来自同一水源的密苏里州堪萨斯城软化水的两倍多。血清胆固醇和甘油三酯水平相似，但堪萨斯州堪萨斯城的血压较高，这与较高的血清钠、较低的血清钾以及高十倍的血清镉有关。堪萨斯州的血清钙和镁水平较高，而密苏里州的铜、铬、钴和锌水平较高。血清研究是对来自每个样本城市的两组各260名匹配的成年人进行的。高血压可能是所观察到的冠心病发病率相反情况的原因，且与镉有关。