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在通过碘乙酸对辐射致敏的过程中，碘掺入细胞成分中。

Iodine incorporated in cell constituents during sensitization to radiation by iodoacetic acid.

作者信息

Shenoy M A, Singh B B, Gopal-Ayengar A R

出版信息

Science. 1968 May 31;160(3831):999. doi: 10.1126/science.160.3831.999.

DOI:10.1126/science.160.3831.999
PMID:4869661
Abstract

Iodine atoms are incorporated in bacterial membrane proteins when cells are irradiated in the presence of iodoacetic acid labeled with iodine-131. Such atoms are produced on reaction of iodoacetic acid with the gamma ray-induced hydroxyl radicals in the surrounding medium.

摘要

当细胞在含有用碘-131标记的碘乙酸的情况下受到辐照时，碘原子会掺入细菌膜蛋白中。这些原子是碘乙酸与周围介质中γ射线诱导产生的羟基自由基反应生成的。

相似文献

1
Iodine incorporated in cell constituents during sensitization to radiation by iodoacetic acid.在通过碘乙酸对辐射致敏的过程中，碘掺入细胞成分中。
Science. 1968 May 31;160(3831):999. doi: 10.1126/science.160.3831.999.
2
Role of bacterial membranes in radiosensitization.细菌膜在放射增敏中的作用。
Adv Biol Med Phys. 1970;13:255-71. doi: 10.1016/b978-0-12-005213-4.50012-0.
3
Radio-sensitization with iodine compounds. II. Studies on mutant strains of Escherichia coli K12 resistant to radiation-induced toxic products from iodoacetic acid, potassium iodide or potassium iodate.碘化合物的放射增敏作用。II. 对辐射诱导的碘乙酸、碘化钾或碘酸钾毒性产物具有抗性的大肠杆菌K12突变菌株的研究。
Int J Radiat Biol Relat Stud Phys Chem Med. 1970 May;17(5):419-30. doi: 10.1080/09553007014550521.
4
Radiosensitization with iodine compounds. 3. Macromolecular synthesis and repair in Bacillus subtilis irradiated in the presence of iodoacetic acid, potassium iodide or potassium iodate.碘化合物的放射增敏作用。3. 在碘乙酸、碘化钾或碘酸钾存在下辐照的枯草芽孢杆菌中的大分子合成与修复。
Int J Radiat Biol Relat Stud Phys Chem Med. 1971;19(4):305-22. doi: 10.1080/09553007114550431.
5
Comparison of the effects of some iodine compounds on the survival of Escherichia coli B-r irradiated with X rays and ultra-violet light.某些碘化合物对经X射线和紫外线照射的大肠杆菌B-r存活影响的比较。
Ann Ist Super Sanita. 1970;6(4):293-301.
6
Production and rejoining of single-strand breaks in DNA of Escherichia coli cells after exposure to gamma-rays in the presence of iodoacetic acid under oxic and anoxic conditions.在有氧和无氧条件下，大肠杆菌细胞DNA在碘乙酸存在下暴露于γ射线后单链断裂的产生与重新连接
Int J Radiat Biol Relat Stud Phys Chem Med. 1976 Mar;29(3):235-40. doi: 10.1080/09553007614550261.
7
Mechanism of the inhibition of germination of bacterial spores by gamma-irradiation in the presence of iodoacetamide and iodate.在碘乙酰胺和碘酸盐存在的情况下，γ射线辐照抑制细菌芽孢萌发的机制
J Gen Microbiol. 1970 Dec;64(3):301-9. doi: 10.1099/00221287-64-3-301.
8
[Radiosensitization by monoiodacetic acid. I. Study of the radiation sensitizing mechanism of monoiodoacetic acid].
Int J Radiat Biol Relat Stud Phys Chem Med. 1967;13(5):433-47. doi: 10.1080/09553006814550461.
9
[Repair of DNA and chemical radiosensitivity: study of the comparative action of caffeine and iodoacetamide on the survival and ultraviolet and gamma reactivation in Escherichia coli K 12/gamma vir].
Int J Radiat Biol Relat Stud Phys Chem Med. 1969;15(4):369-84. doi: 10.1080/09553006914550591.
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Sensitization of damage by ultra-violet light to mammalian erythrocyte membrane.紫外线对哺乳动物红细胞膜损伤的致敏作用。
Ann Ist Super Sanita. 1970;6(4):302-9.

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