Parkhouse J, Mahoney J
Postgrad Med J. 1968 Mar;44(509):229-33. doi: 10.1136/pgmj.44.509.229.
A state-registered nurse acted as a whole-time investigator following patients through the pre-operative night in hospital and questioning them in the morning, to assess the relative merits of different medications. Two new sedatives were compared with a standard barbiturate and a placebo, and information was collected from patients who elected to have no medication to help them sleep. Subjective assessment enabled the placebo to be distinguished from the active medications, although there was little difference between these. The importance of psychological factors is discussed in relation to those patients who had no medication.
一名注册护士作为全职调查员，在患者住院的术前一晚对其进行跟踪，并在早晨对他们进行询问，以评估不同药物的相对优点。将两种新型镇静剂与一种标准巴比妥酸盐和一种安慰剂进行比较，并从选择不服用任何助眠药物的患者那里收集信息。主观评估能够区分安慰剂和活性药物，尽管它们之间差异不大。针对那些未用药的患者，讨论了心理因素的重要性。
