Shahid Salles M S, Heym J, Gladfelter W E
Brain Res Bull. 1979 Sep-Oct;4(5):643-9. doi: 10.1016/0361-9230(79)90107-2.
The effects of damage to the median raphe nucleus on the ingestive behavior and wheel running activity of rats were studied. This nucleus was damaged by the placement of either electrolytic or chemical (5,7-dihydroxytryptamine) lesions. After the placement of either type of lesion, wheel running activity was significantly decreased for the duration of the 8 week post-operative period. Although there were transient decreases in both food and water intakes after damage to the median raphe nucleus, these decreases did not appear to result from impairments in neuro-regulatory mechanisms. Rather, the decrease in food intake seemed to be related to the decrease in locomotor activity, and the decrease in water intake appeared to be linked to the decrease in food intake. In some rats with electrolytic lesions in the median raphe nucleus, the decrease in water intake was followed by a transient period of hyperdipsia.
研究了中缝核损伤对大鼠摄食行为和转轮活动的影响。通过放置电解或化学（5,7-二羟基色胺）损伤来损伤该核。在放置任何一种类型的损伤后，在术后8周的时间内，转轮活动显著降低。虽然中缝核损伤后食物和水的摄入量都有短暂下降，但这些下降似乎并非由神经调节机制受损所致。相反，食物摄入量的下降似乎与运动活动的减少有关，而水摄入量的下降似乎与食物摄入量的减少有关。在一些中缝核有电解损伤的大鼠中，水摄入量下降后会有一段短暂的多饮期。
