Asin K E, Wirtshafter D
Physiol Behav. 1982 Jan;28(1):89-93. doi: 10.1016/0031-9384(82)90108-1.
The current study examines the effects of electrolytic median raphe lesions on the feeding and drinking behaviors of rats maintained on a 23-hr food deprivation schedule. Measurement of food intake during the feeding period indicated no difference between the two groups but lesioned animals showed significantly more spillage than controls. Furthermore, measurement of water intakes indicated that median raphe lesioned rats consume significantly less water than controls in the absence of food and come to ingest virtually all of their daily fluid intake during the feeding period. Additionally, rats with lesions of this nucleus take significantly more drinks during the feeding period, often punctuating their meal with short draughts. Since similar behaviors are seen following the destruction of certain hypothalamic and limbic nuclei anatomically related to the median raphe, it is possible that these syndromes share an anatomical basis.
当前的研究考察了电解中缝核损伤对按23小时食物剥夺时间表饲养的大鼠进食和饮水行为的影响。对进食期间食物摄入量的测量表明两组之间没有差异，但损伤组动物的食物溢出量显著多于对照组。此外，对水摄入量的测量表明，中缝核损伤的大鼠在无食物时的饮水量显著少于对照组，并且几乎所有的日液体摄入量都在进食期间摄入。另外，该核损伤的大鼠在进食期间饮水次数显著更多，常常在进食过程中短暂饮水。由于在破坏与中缝核在解剖学上相关的某些下丘脑和边缘核后也观察到类似行为，因此这些综合征可能有共同的解剖学基础。
