Thompson C E, Ashurst P M, Butler T J
Br Med J. 1968 Aug 3;3(5613):283-5. doi: 10.1136/bmj.3.5613.283.
Fluorescent-antibody studies in 22 patients out of a total of 40 cases of acute erosive gastritis showed no antibodies to gastric parietal cells. Hence erosive gastritis seems unlikely to be an autoimmune phenomenon.In this series 57.5% of cases belonged to blood group A. This suggests that there is a correlation between the instability of the gastric mucosa and blood group A.The operative mortality in erosive gastritis is high. Operation should be delayed as long as possible in the hope that the bleeding will stop spontaneously. Erosive gastritis may be idiopathic or precipitated by drugs, particularly aspirin. The highest risk was found to occur in those cases where bleeding was drug-induced.
在40例急性糜烂性胃炎患者中的22例进行的荧光抗体研究显示,没有针对胃壁细胞的抗体。因此,糜烂性胃炎似乎不太可能是一种自身免疫现象。在这个系列中,57.5%的病例属于A型血。这表明胃黏膜的不稳定性与A型血之间存在关联。糜烂性胃炎的手术死亡率很高。应尽可能推迟手术,希望出血能自行停止。糜烂性胃炎可能是特发性的,也可能由药物诱发,尤其是阿司匹林。研究发现,药物引起出血的那些病例风险最高。