急性心肌梗死时3-甲氧基-4-羟基苯乙二醇的尿排泄情况

The urinary excretion of 3-methoxy-4-hydroxyphenylglycól in acute myocardial infarction.

作者信息

Wocial B, Sznajderman M, Januszewicz W, Raczyński J

出版信息

Clin Chim Acta. 1979 Aug 1;95(3):517-20. doi: 10.1016/0009-8981(79)90204-3.

Abstract

Urinary excretion of 3-methoxy-4-hydroxyphenylglycol (MHPG), noradrenaline, adrenaline and vanillylmandelic acid (VMA) was studied in 30 patients with acute myocardial infarction. The excretion of MHPG was higher in patients with myocardial infarction than in the control group, with no difference between uncomplicated and complicated courses of the disease. The excretion of MHPG showed a negative although not significant correlation with noradrenaline and VMA during the first days of infarction and a statistically significant positive correlation on the 5th day of the disease. The possible causes of the changes observed are discussed.

摘要

对30例急性心肌梗死患者的3-甲氧基-4-羟基苯乙二醇（MHPG）、去甲肾上腺素、肾上腺素和香草扁桃酸（VMA）的尿排泄情况进行了研究。心肌梗死患者的MHPG排泄量高于对照组，疾病的非并发症和并发症病程之间无差异。在梗死的最初几天，MHPG的排泄量与去甲肾上腺素和VMA呈负相关，虽不显著，但在疾病第5天时呈统计学显著正相关。讨论了观察到的这些变化的可能原因。