Shormanov S V
Cor Vasa. 1979;21(2):117-23.
The rebuilding of pulmonary vessels at hypo- and hypertension in the lesser circulation was studied in 41 puppy dogs, in which hypotension had been induced by stenosing the pulmonary artery. Eighteen animals were successively sacrificed 6--9 months after the surgery. Histological examinations revealed atrophic and sclerotic lesions of the pulmonary arteries. In the remaining 23 animals, various anastomoses were formed between the systemic and pulmonary circulation systems, which led to the formation of hypertrophic and hyperplastic alterations in the pulmonary vessels and to pulmonary hypertension.
在41只幼犬中研究了小循环低血压和高血压时肺血管的重建情况,这些幼犬的肺动脉已通过狭窄造成低血压。术后6至9个月,相继处死18只动物。组织学检查显示肺动脉有萎缩和硬化病变。在其余23只动物中,体循环和肺循环系统之间形成了各种吻合,导致肺血管出现肥厚和增生性改变以及肺动脉高压。