Bolotovskij V M, Zetilova L P
Bull World Health Organ. 1968;39(2):293-8.
This study is another in the WHO series of comparisons of measles vaccines prepared from different strains of virus. The Leningrad-16 strain was compared with the Schwarz strain in a trial with children aged 1 to 6 years. A group inoculated with placebo was included as a control.Pyrexias and rashes were more common in the Leningrad-16 group than in the Schwarz group but in neither were the reactions serious. Antibody responses were good in both groups.During the 12 months after vaccination, measles occurred in 5% of the children known to have been exposed to infection in the Leningrad-16 group, 6% in the Schwarz group and 58% in the control group.
本研究是世界卫生组织关于不同病毒株制备的麻疹疫苗比较系列中的另一项研究。在一项针对1至6岁儿童的试验中，对列宁格勒-16株疫苗和施瓦茨株疫苗进行了比较。将接种安慰剂的一组作为对照。列宁格勒-16组的发热和皮疹比施瓦茨组更常见，但两组的反应都不严重。两组的抗体反应都良好。在接种疫苗后的12个月内，已知接触过感染源的儿童中，列宁格勒-16组有5%患麻疹，施瓦茨组有6%，对照组有58%。
