Gunter A C, Feary T W
J Bacteriol. 1968 Nov;96(5):1556-61. doi: 10.1128/jb.96.5.1556-1561.1968.
Of 398 strains of clinically isolated Escherichia coli from three Birmingham, Alabama, hospitals, 38% were found to be resistant to one or more drugs tested. Fifty-seven per cent of the resistant strains transferred all or a part of their resistance pattern to sensitive cells during mixed cultivation. Of the 152 resistant strains, 29.1% were singly resistant, and 70.5% were resistant to more than one drug. Of the multiply resistant strains, 61% transferred all or a part of their pattern. Strains isolated from Veterans Hospital patients demonstrated higher percentages of resistance than strains isolated from Children's Hospital patients. An extremely low incidence of infective drug resistance was noted among E. coli isolated from the stools of healthy hospital employees.
在从阿拉巴马州伯明翰市的三家医院临床分离出的398株大肠杆菌中，发现38%的菌株对一种或多种测试药物具有抗性。在混合培养过程中，57%的抗性菌株将其全部或部分抗性模式转移至敏感细胞。在152株抗性菌株中，29.1%为单一抗性，70.5%对不止一种药物具有抗性。在多重抗性菌株中，61%转移了其全部或部分抗性模式。从退伍军人医院患者中分离出的菌株显示出比从儿童医院患者中分离出的菌株更高的抗性百分比。在从健康医院员工粪便中分离出的大肠杆菌中，观察到感染性耐药的发生率极低。
