Fischman A
Bull World Health Organ. 1968;39(1):39-43.
The sensitivity of indirect agglutination tests for the diagnosis of human hydatid disease, although high, is not sufficient. Furthermore, the general use of hydatid fluid as antigen is responsible for some false positive reactions. Scolex extracts have been shown to increase specificity, but less attention has been paid to whole-scolex antigens. The author describes a new whole-scolex complement-fixation test that, like other scolex tests, is more specific than tests using fluid antigen. Its sensitivity is at least equal to that of the hydatid fluid latex-agglutination test, and is higher than that of the fluorescent-antibody, the scolex extract latex, and the hydatid fluid complement-fixation tests.The new test is also of interest since particulate antigens are uncommon, compared with soluble antigens, in complement-fixation techniques.
间接凝集试验用于诊断人类包虫病，其敏感性虽高，但仍不足够。此外，普遍使用包虫囊液作为抗原会导致一些假阳性反应。已证明头节提取物可提高特异性，但对全头节抗原的关注较少。作者描述了一种新的全头节补体结合试验，与其他头节试验一样，该试验比使用囊液抗原的试验更具特异性。其敏感性至少与包虫囊液乳胶凝集试验相当，且高于荧光抗体试验、头节提取物乳胶试验和包虫囊液补体结合试验。这种新试验也很有意义，因为在补体结合技术中，与可溶性抗原相比，颗粒性抗原并不常见。
