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Changes in serum proteins and in major liver constituents following carbon tetrachloride and a high-fat choline-free diet in rats.

作者信息

Agostini C, Alfisi M

出版信息

Experientia. 1979 Sep 15;35(9):1225-6. doi: 10.1007/BF01963304.

DOI:10.1007/BF01963304
PMID:488288
Abstract

Both carbon tetrachloride and a high-fat, low-protein choline-free diet cause hepatomegaly in rats due to an accumulation of both lipids and proteins with a concomitant increase in deoxyribonucleic acid content. CCl4 causes a decline in hepatic glycogen. Serum albumin level is decreased in CCl4-treated rats and increased in those fed the experimental diet.

摘要

相似文献

1
Changes in serum proteins and in major liver constituents following carbon tetrachloride and a high-fat choline-free diet in rats.
Experientia. 1979 Sep 15;35(9):1225-6. doi: 10.1007/BF01963304.
2
Biochemical changes in isolated perfused livers from rats intoxicated with CCl4 or fed with steatogenous diet.四氯化碳中毒或喂食致脂肪生成饮食的大鼠离体灌注肝脏中的生化变化。
Pharmacol Res Commun. 1980 Apr;12(4):295-306. doi: 10.1016/s0031-6989(80)80086-5.
3
Effect of long-term administration of ethanol to the rat: lipids, collagen and other proteins, and Mallory bodies in the liver.长期给大鼠注射乙醇的影响：肝脏中的脂质、胶原蛋白及其他蛋白质，以及马洛里小体。
Scand J Clin Lab Invest. 1975 Dec;35(8):753-65. doi: 10.3109/00365517509095807.
4
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Vopr Med Khim. 1966 Nov-Dec;12(6):627-32.
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Effects of long-term treatment of rats with ethanol, carbon tetrachloride and high fat-low protein diet on the Kupffer cell distribution with reference to chemical composition of the liver.
Acta Pathol Microbiol Immunol Scand C. 1983 Jun;91(3):221-5.
6
Does oxidative protein damage play a role in the pathogenesis of carbon tetrachloride-induced liver injury in the rat?氧化蛋白质损伤在四氯化碳诱导的大鼠肝损伤发病机制中起作用吗？
Biochim Biophys Acta. 1997 Dec 31;1362(2-3):169-76. doi: 10.1016/s0925-4439(97)00065-3.
7
[Effect of pyrogenal and glucomannan on the liver content of peptides and nucleopeptides and blood protein content in CC14-hepatitis in rats].[热原质和葡甘露聚糖对四氯化碳诱导的大鼠肝炎中肝脏肽和核肽含量及血液蛋白质含量的影响]
Vopr Med Khim. 1972 Nov-Dec;18(6):627-30.
8
[Changes in the protein content and transaminase activity of the liver and blood serum of rats administered low doses of antihepatocytotoxic serum against a background of acute carbon tetrachloride lesion of the liver].[在急性四氯化碳肝损伤背景下，给大鼠注射低剂量抗肝细胞毒性血清后肝脏和血清中蛋白质含量及转氨酶活性的变化]
Ukr Biokhim Zh. 1973 May-Jun;45(3):254-7.
9
Effect of methotrexate on long-chain fatty acid metabolism in liver of rats fed a standard or a defined, choline-deficient diet.甲氨蝶呤对喂食标准或特定胆碱缺乏饮食的大鼠肝脏中长链脂肪酸代谢的影响。
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An ω-3-enriched diet alone does not attenuate CCl-induced hepatic fibrosis.仅富含ω-3的饮食并不能减轻四氯化碳诱导的肝纤维化。
J Nutr Biochem. 2016 Dec;38:93-101. doi: 10.1016/j.jnutbio.2016.08.010. Epub 2016 Sep 14.

本文引用的文献

1
The effects of short-term changes in dietary protein on the response of the liver to carbon tetrachloride injury.饮食蛋白质短期变化对肝脏四氯化碳损伤反应的影响。
Br J Exp Pathol. 1948 Apr;29(2):149-59.
2
[Variations of composition of the fatty liver due to chemical poisons. Criteria for correct evaluation of experimental data].[化学毒物所致脂肪肝的成分变化。正确评估实验数据的标准]
Sperimentale. 1959 Sep-Oct;109:459-70.
3
Release of catechol amines from the adrenal medulla by carbon tetrachloride.四氯化碳引起肾上腺髓质释放儿茶酚胺。
Am J Physiol. 1960 Mar;198:682-5. doi: 10.1152/ajplegacy.1960.198.3.682.
4
Toxic fatty liver in adrenalectomized rats.肾上腺切除大鼠的中毒性脂肪肝
Br J Exp Pathol. 1960 Dec;41(6):617-22.
5
The effect of metabolic disturbance on cystine-S35 partition among rat liver cytostructures.代谢紊乱对大鼠肝脏细胞结构中胱氨酸-S35分配的影响。
J Biol Chem. 1953 Jan;200(1):451-9.
6
Considerations on the pathogenesis of fatty liver.关于脂肪肝发病机制的思考
Lab Invest. 1966 Jan;15(1 Pt 1):1-20.
7
Effects of choline deficiency on rat hepatocytes.胆碱缺乏对大鼠肝细胞的影响。
Fed Proc. 1971 Jan-Feb;30(1):139-42.
8
Determination of glycogen in small tissue samples.小组织样本中糖原的测定。
J Appl Physiol. 1970 Feb;28(2):234-6. doi: 10.1152/jappl.1970.28.2.234.
9
Triglyceride levels and oxygen consumption of liver, kidney and heart following a high fat choline free diet in rats.大鼠高脂无胆碱饮食后肝脏、肾脏和心脏的甘油三酯水平及氧消耗量
Pathol Eur. 1973;8(2):105-11.
10
Biosynthesis of rat serum albumin. VII. Effects observed in liver slices.大鼠血清白蛋白的生物合成。VII. 在肝切片中观察到的效应。
Am J Physiol. 1973 Jun;224(6):1363-8. doi: 10.1152/ajplegacy.1973.224.6.1363.