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嗜酸性肉芽肿的体外胶原溶解活性

Collagenolytic activity of eosinophilic granuloma in vitro.

作者信息

Rousseau-Merck M F, Barbey S, Mouly H, Bazin S, Nezelof C

出版信息

Experientia. 1979 Sep 15;35(9):1226-8. doi: 10.1007/BF01963305.

Abstract

Lytic activity of eosinophilic granuloma and other tumours was studied in vitro on collagen substrate. Collagen degradation was measured through the release of hydroxyproline-rich peptides into the medium. The in vitro lytic action was at a maximum in the case of EG and was correlated with the presence of histiocytic cells.

摘要

在体外对胶原底物研究了嗜酸性肉芽肿及其他肿瘤的溶解活性。通过向培养基中释放富含羟脯氨酸的肽来测定胶原降解。在嗜酸性肉芽肿的情况下,体外溶解作用最强,且与组织细胞的存在相关。

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