Frohman L A, Nernardis L L, Kant K J
Science. 1968 Nov 1;162(3853):580-2. doi: 10.1126/science.162.3853.580.
Stimulation of the ventromedial hypothalamic nucleus in rats resulted in increased plasma growth hormone levels within 5 minutes, as measured by radioimmunoassay. Stimulation of the cerebral cortex was without effect. These observations confirm previous results involving destructive lesions and establish the ventromedial nucleus as a hypothalamic locus involved in the control of growth hormone secretion.
通过放射免疫测定法检测发现,刺激大鼠腹内侧下丘脑核会导致5分钟内血浆生长激素水平升高。刺激大脑皮层则没有效果。这些观察结果证实了先前涉及破坏性损伤的研究结果,并确定腹内侧核是参与控制生长激素分泌的下丘脑位点。