丹麦人类红细胞乙二醛酶I多态性及其在亲子鉴定案例中的应用。

Human red cell glyoxalase I polymorphism in Denmark and its application to paternity cases.

作者信息

Eriksen B

出版信息

Hum Hered. 1979;29(5):265-71. doi: 10.1159/000153056.

Abstract

Phenotypes of glyoxalase I (GLO) were determined in 1220 unrelated adults from all parts of Denmark giving the gene frequencies GLO1 = 0.4311 and GLO2 = 0.5689. The segregation of phenotypes in 59 families and in 455 mother-child pairs was consistent with the assumed autosomal codominant inheritance. The results of an investigation of 379 parternity cases with respect to exclusions of non-fathers by means of the GLO system are reported, and the application of the GLO system to paternity cases is discussed.

摘要

在来自丹麦各地的1220名无亲缘关系的成年人中测定了乙二醛酶I（GLO）的表型，得出基因频率GLO1 = 0.4311和GLO2 = 0.5689。59个家庭和455对母婴对中表型的分离与假定的常染色体共显性遗传一致。报告了一项关于379例亲子关系案例的调查结果，该调查通过GLO系统排除非父亲，并且讨论了GLO系统在亲子鉴定案例中的应用。