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[对塞格德及其周边地区(匈牙利南部)居民的乙二醛酶I(GLO)红细胞同工酶系统进行群体遗传学检测(作者译)]

[Population-genetic examination of the glyoxalase I (GLO) red-cell isoenzyme system in the inhabitants of Szeged and its environment (South-Hungary) (author's transl)].

作者信息

Kósa F, Fekete-Csete K, Földes V

出版信息

Z Rechtsmed. 1982;88(1-2):113-9. doi: 10.1007/BF00200743.

Abstract

The authors have examined the gene frequency and phenotype distribution of GLO isoenzyme system in the blood samples from 1,288 randomized, unrelated persons and from 151 mother-child pairs by horizontal starch-gel electrophoresis. The observed gene frequencies (GLO1 = 0.3990, GLO2 = 0.6009) and phenotype distributions (GLO 1 = 18.1%; GLO 2-1 = 43.79%; GLO 2 = 38.20%) were in good accordance with that of the Caucasian population. The authors did not find any difference from the genetic model of two codominant alleles at an autosomal locus. The theoretical exclusion rate in paternity cases based on the GLO gene frequencies is 18.23%.

摘要

作者通过水平淀粉凝胶电泳检测了1288名随机选取的无血缘关系个体以及151对母婴的血液样本中GLO同工酶系统的基因频率和表型分布。观察到的基因频率(GLO1 = 0.3990,GLO2 = 0.6009)和表型分布(GLO 1 = 18.1%;GLO 2-1 = 43.79%;GLO 2 = 38.20%)与白种人群体的情况高度一致。作者未发现常染色体位点上两个共显性等位基因的遗传模型存在任何差异。基于GLO基因频率的亲子鉴定理论排除率为18.23%。

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