Callen J P
Int J Dermatol. 1979 Jul-Aug;18(6):423-33. doi: 10.1111/j.1365-4362.1979.tb01945.x.
Dermatomyositis and polymyositis are diseases which must be carefully defined in each patient. Criteria such as those suggested by Bohan and Peter will help define the disease and exclude other possible causes of myositis. Immunological factors are probably involved in the pathogenesis of the disease, although varied types of injury may manifest in clinically similar disease. Dermatomyositis, not polymyositis, is related to internal malignancy in adults; however, an extensive malignancy evaluation is not indicated. Therapy with corticosteroids will improve the quality of life, will prevent contractures and calcinosis and may improve the chance of survival. In cases where steroids are ineffective, immunosuppressives may be helpful.
皮肌炎和多发性肌炎是必须在每位患者中仔细界定的疾病。诸如博汉和彼得所建议的那些标准将有助于明确该疾病,并排除其他可能的肌炎病因。免疫因素可能参与了该疾病的发病机制,尽管不同类型的损伤可能在临床上表现为相似的疾病。皮肌炎而非多发性肌炎与成人的内脏恶性肿瘤有关;然而,并不需要进行广泛的恶性肿瘤评估。使用皮质类固醇进行治疗将改善生活质量,预防挛缩和钙质沉着,并可能提高生存几率。在类固醇治疗无效的情况下,免疫抑制剂可能会有所帮助。