Ulshöfer B, Joseph K, Rodeck G
Helv Chir Acta. 1979 Aug;46(3):399-403.
The serum levels of total calcium and anorganic phosphate have been the leading parameters in the diagnosis of primary hyperparathyroidism. In addition to these, it is now possible to measure ionized calcium (Ca++) by an ion-selective electrode and parathormone (PTH) by C- and N-terminal radioimmunoassays (RIA). Whereas Ca++ determination and C-terminal PTH RIA represent a diagnostic progress, this can not be claimed for the N-terminal PTH RIA in peripheral venous blood especially in border-line cases.
血清总钙和无机磷水平一直是原发性甲状旁腺功能亢进症诊断的主要指标。除此之外,现在可以通过离子选择电极测量离子钙(Ca++),并通过C端和N端放射免疫分析法(RIA)测量甲状旁腺激素(PTH)。虽然Ca++测定和C端PTH RIA代表了诊断上的进步,但外周静脉血中N端PTH RIA却并非如此,尤其是在临界病例中。