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基于颈部静脉血中甲状旁腺激素测定的原发性甲状旁腺功能亢进症的诊断(作者译)

[Diagnosis of primary hyperparathyroidism based on determination of parathormone in venous blood of the neck (author's transl)].

作者信息

Bressel M, Christensen P, Dorn G, Hagemann J, Josten K, Montz R

出版信息

Urologe A. 1978 Jan;17(1):29-33.

PMID:625852
Abstract

Experiences with 77 patients with primary hyperparathyroidism (HPT) are reported. Among the diagnostic parameters, the serum calcium level is the most significant; a definite diagnosis can be made through PTH-RIA. The problem of HPT diagnosis are discussed. For standardization, our own human PTH preparation, produced from tissue culture of operatively removed human adenoma of the parathyroid gland, has been used. For determination of parathormone, venous blood should be selectively extracted from the neck before every relapse-necessitated operation. The technically expensive and difficult examination methods do not excuse the surgeon from carefully exploring all of the parathyroid glands, though the general procedures to be applied before the first operation are still disputed.

摘要

报告了77例原发性甲状旁腺功能亢进症(HPT)患者的经验。在诊断参数中,血清钙水平最为重要;通过甲状旁腺激素放射免疫分析(PTH-RIA)可做出明确诊断。讨论了HPT的诊断问题。为实现标准化,我们使用了从手术切除的人甲状旁腺腺瘤组织培养中制备的人甲状旁腺激素制剂。为测定甲状旁腺激素,每次因复发而需要手术前,都应从颈部选择性抽取静脉血。尽管首次手术前应采用的一般程序仍存在争议,但技术上昂贵且困难的检查方法并不能免除外科医生仔细探查所有甲状旁腺的责任。

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