Hadas E, Sadé J
J Laryngol Otol. 1979 Aug;93(8):781-3. doi: 10.1017/s0022215100087715.
This is a study of the rate of middle ear clearance in chronic otitis media and atelectatic ears. The clearance rate was measured with the aid of non-soluble saccharin, introduced into the middle ear through an existing perforation in 'chronic ears', or through a ventilating tube in atelectatic ears. Cholesteatomatous ears were excluded. Altogether 122 ears were examined and about two-thirds of the subjects felt the sweet taste in their mouths thereafter. The average time it took for the saccharin to be transported from the middle ear to the taste buds was 33' 22" minutes in non-infected (i.e. dry) chronic ears (38 patients or 66 per cent). Wet or infected ears with chronic otitis media (30 patients, or 58 per cent) showed a slower transport rate, averaging 54' 22" minutes--the difference was significant at the 0.01 level. 8 (63 per cent) of the atelectatic ears transported the saccharin at an average rate of 50' 25". This study demonstrated that most ears with 'simple' chronic otitis media and atelectatic ears have a patent eustachian tube and that their mucociliary system can transport foreign particles through it. When the ear is infected, transport tends to be slowed down.
这是一项关于慢性中耳炎和萎缩性耳中耳清除率的研究。清除率借助不溶性糖精进行测量，糖精通过“慢性耳”现有的穿孔引入中耳，或通过萎缩性耳的通气管引入中耳。胆脂瘤性耳被排除在外。总共检查了122只耳朵，此后约三分之二的受试者在口中尝到了甜味。在未感染（即干燥）的慢性耳（38例患者，占66%）中，糖精从中耳传输到味蕾的平均时间为33分22秒。慢性中耳炎的湿性或感染性耳（30例患者，占58%）显示传输速度较慢，平均为54分22秒——差异在0.01水平上具有显著性。8只（63%）萎缩性耳传输糖精的平均速度为50分25秒。这项研究表明，大多数患有“单纯性”慢性中耳炎和萎缩性耳的耳朵咽鼓管通畅，其黏液纤毛系统能够通过咽鼓管运输外来颗粒。当耳朵感染时，传输往往会减慢。
