Birge E A, Kurland C G
Science. 1969 Dec 5;166(3910):1282-4. doi: 10.1126/science.166.3910.1282.
We have compared the 30S ribosomal proteins of strains of Escherichia coli sensitive to and dependent on streptomycin and identified a single protein that is functionally altered in the ribosomes dependent on streptomycin. This protein (30S-15) is the same protein that is functionally altered in ribosomes resistant to streptomycin.
我们比较了对链霉素敏感和依赖链霉素的大肠杆菌菌株的30S核糖体蛋白,并鉴定出一种在依赖链霉素的核糖体中功能发生改变的单一蛋白。这种蛋白(30S-15)与在对链霉素耐药的核糖体中功能发生改变的蛋白相同。