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两种不同品系小鼠对鼠伤寒沙门氏菌抗原的反应。

The response to Salmonella typhimurium antigens by two different strains of mice.

作者信息

Auzins I, Rowley D

出版信息

Immunology. 1969 Oct;17(4):579-85.

Abstract

A technique is described for the detection and enumeration of cells producing antibody to O-somatic antigen specificities 1, 4, 5 and 12 of . Using this technique, a difference in the immune response has been demonstrated between Swiss White and the BALB/c strain mice, when both these strains are injected with a standard dose of acetone-killed C5 vaccine. BALB/c mice fail to respond to antigen 5 and their response to the 1, 4 and 12 O-somatic antigens, while reaching the same magnitude, is less prolonged than that in Swiss White mice.

摘要

本文描述了一种用于检测和计数针对[细菌名称]O-菌体抗原特异性1、4、5和12产生抗体的细胞的技术。使用该技术,当给瑞士白化小鼠和BALB/c品系小鼠注射标准剂量的丙酮灭活[细菌名称]C5疫苗时,已证明这两个品系小鼠的免疫反应存在差异。BALB/c小鼠对抗原5无反应,它们对1、4和12 O-菌体抗原的反应虽然达到相同程度,但持续时间比瑞士白化小鼠短。

相似文献

3
Mechanisms in antimicrobial immunity.抗菌免疫机制。
J Reticuloendothel Soc. 1971 Jul;10(1):58-99.

本文引用的文献

10
A comparative assay of O-somatic antigen 5 of Salmonellae.沙门氏菌O-菌体抗原5的比较测定
Aust J Exp Biol Med Sci. 1968 Feb;46(1):93-105. doi: 10.1038/icb.1968.8.

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