速释铁与缓释铁：每日单剂量方案的双盲试验
Quick- and slow-release iron: a double-blind trial with a single daily dose regimen.
作者信息
Callender S T
出版信息
Br Med J. 1969 Nov 29;4(5682):531-2. doi: 10.1136/bmj.4.5682.531.
Abstract
In a double-blind trial the response to treatment with Ferro-Gradume (a slow-release preparation of ferrous sulphate) has been compared in the same individuals with the response to ferrous fumarate in a single daily dose regimen using a similar dose of iron. No significant difference was found in the therapeutic response or in the incidence of side-effects between the two preparations.
摘要
在一项双盲试验中，对同一组个体使用相似剂量的铁，比较了他们对Ferro-Gradume（硫酸亚铁缓释制剂）治疗的反应与对富马酸亚铁每日单次剂量疗法的反应。两种制剂在治疗反应或副作用发生率方面均未发现显著差异。
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本文引用的文献
1
A TRIAL OF SLOW-RELEASE TABLETS OF FERROUS SULPHATE.硫酸亚铁缓释片试验
Curr Ther Res Clin Exp. 1965 Apr;7:244-8.
2
Treatment of anemia in obstetric and gynecologic patients with sustained-release and conventional iron preparations.使用缓释铁制剂和传统铁制剂治疗妇产科患者的贫血症。
Obstet Gynecol. 1966 Sep;28(3):430-4.
3
Absorption of therapeutic preparations of iron measured with a whole body counter.用全身计数器测量铁治疗制剂的吸收情况。
Br Med J. 1969 Nov 29;4(5682):532-4. doi: 10.1136/bmj.4.5682.532.
4
New preparations for oral iron-therapy.口服铁疗法的新制剂。
Lancet. 1965 Oct 2;2(7414):654-7. doi: 10.1016/s0140-6736(65)90394-6.
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