DeAmicis L A, Cromwell R L
J Nerv Ment Dis. 1979 Oct;167(10):593-600. doi: 10.1097/00005053-197910000-00002.
Of 70 process schizophrenic patients clinically assessed and tested for reaction time, 40 showed reaction time crossover. Of the 40 with crossover, 53 of their first degree relatives were clinically assessed and tested. Five of the relatives, found to have psychotic symptoms, were analyzed separately. Also, 41 control subjects without personal or family history of psychiatric disturbance were clinically assessed and tested. The nondisturbed relatives had reaction time crossover (regular minus irregular) significantly greater than the (expected) negative values of the normal control subjects, but not significantly greater than a zero value within subjects. When disturbed and nondisturbed relatives were combined, greater differences indicative of crossover occurred. On the other hand, the relatives, as expected, did not show the slow mean reaction time characteristic of diagnosed schizophrenic patients.
在70名接受临床评估并进行反应时间测试的过程型精神分裂症患者中，40名出现了反应时间交叉。在这40名有交叉的患者中，对其53名一级亲属进行了临床评估和测试。发现有5名亲属有精神病症状，对他们进行了单独分析。此外，对41名无个人或家族精神障碍病史的对照受试者进行了临床评估和测试。未受干扰的亲属的反应时间交叉（规则减去不规则）显著大于正常对照受试者的（预期）负值，但不显著大于受试者内部的零值。当受干扰和未受干扰的亲属合并时，出现了更明显的表明交叉的差异。另一方面，正如预期的那样，亲属并未表现出已确诊精神分裂症患者所特有的平均反应时间缓慢的特征。
