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支气管肺发育不良——病理学

Bronchopulmonary dysplasia--pathology.

作者信息

Reid L

出版信息

J Pediatr. 1979 Nov;95(5 Pt 2):836-41. doi: 10.1016/s0022-3476(79)80446-1.

Abstract

The term bronchopulmonary dysplasia has much to commend it. It does not declare the etiology of this disease, which seems to be an advantage. Another advantage is that it presents the idea of disturbance of growth as well as scarring. The premature lung responds at birth somewhat differently from the mature lung, not just in respect to surfactant but from the point of view of the blood vessels' size and compliance. But treatment must also be considered. The administration of steroids to the mother in the antenatal period probably favors maturation in the fetus, rather than growth of size and cell multiplication, which will also influence the behavior of the lung postnatally. This is probably a critical feature to look for in clinical assessment and follow-up of these patients.

摘要

支气管肺发育不良这个术语有很多值得称赞之处。它没有表明这种疾病的病因,这似乎是一个优点。另一个优点是它既体现了生长紊乱的概念,也体现了瘢痕形成的概念。早产肺在出生时的反应与成熟肺有所不同,不仅在表面活性剂方面,而且从血管大小和顺应性的角度来看也是如此。但治疗也必须加以考虑。产前给母亲使用类固醇可能有利于胎儿成熟,而不是促进大小增长和细胞增殖,这也会影响产后肺的表现。这可能是在对这些患者进行临床评估和随访时需要寻找的一个关键特征。

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