Wycoff C C
Calif Med. 1969 Dec;111(6):423-32.
The data presented in this review have substantiated the following ideas:* There is a direct relationship between digitalis dosage and myocardial contractile force. A small dose of digitalis produces a small increase of the contractile force of the heart and a large dose increases the force of the heart's contraction by a much greater amount, whether the heart is normal, has a poor reserve, or is in frank failure.* Digitalis is of benefit to the patient with cardiovascular disease whether his heart is in failure or not.
*洋地黄剂量与心肌收缩力之间存在直接关系。无论心脏是正常的、储备功能差还是处于明显的衰竭状态，小剂量洋地黄会使心脏收缩力有小幅增加，大剂量则会使心脏收缩力有更大幅度的增加。*无论心血管疾病患者的心脏是否处于衰竭状态，洋地黄对其都有益处。
