Schwartz H C, Olson D J
Oral Surg Oral Med Oral Pathol. 1975 Jun;39(6):837-43. doi: 10.1016/0030-4220(75)90101-2.
Amyloidosis and its oral manifestations are briefly described. The techniques for antemortem tissue diagnosis of amyloidosis are reviewed and evaluated. In screening for amyloidosis, biopsy of specific oral lesions (when present) is recommended instead of the traditional biopsy of normal-appearing gingiva. This approach is illustrated with four cases. Although rectal biopsy is generally accepted as the screening technique of choice, it is suggested that intraoral biopsy be considered as an easier, safer, more comfortable, and possibly more fruitful technique. It is advocated that in cases of both documented and suspected amyloidosis both intraoral and rectal biopsies should be performed in order to help provide documentation of the most useful technique for routine screening.
本文简要描述了淀粉样变性及其口腔表现。对淀粉样变性的生前组织诊断技术进行了综述和评估。在淀粉样变性的筛查中，建议对特定口腔病变（如有）进行活检，而非传统的外观正常牙龈活检。通过四个病例说明了这种方法。虽然直肠活检通常被认为是首选的筛查技术，但建议考虑将口腔内活检作为一种更简便、更安全、更舒适且可能更有成效的技术。提倡在已确诊和疑似淀粉样变性的病例中，均应进行口腔内和直肠活检，以帮助确定常规筛查中最有用的技术。
