Hall M J, Hassall C H
Appl Microbiol. 1970 Jan;19(1):109-12. doi: 10.1128/am.19.1.109-112.1970.
Methods are described for the production of the monamycins by Streptomyces jamaicensis in shake flasks and jar fermentors. The effects on the fermentation of variations in pH, temperature, medium composition, volume of inoculum, and strain of the organism are discussed. The methods employed for the extraction and for the microbiological assay of the antibiotics are outlined.
描述了牙买加链霉菌在摇瓶和罐式发酵罐中生产单霉素的方法。讨论了pH值、温度、培养基组成、接种量和菌株变异对发酵的影响。概述了用于抗生素提取和微生物测定的方法。