Rifkind S, Waisman J, Thompson R, Goldfinger D
JAMA. 1979 Nov 23;242(21):2317-8.
An intermittent-flow blood cell separator was used to perform a sub-total RBC exchange pheresis with prompt relief or priapism secondary to sickle cell disease. The blood cell separator offers an efficient, practical, safe method of performing exchange transfusion in the adult. Surgical procedures in the treatment of priapism have met with limited success and carry a 50% rate of subsequent impotence. We believe that RBC exchange pheresis offers a superior approach in the treatment of complications of sickle cell crisis, including priapism, and should be instituted in the symptomatic patient before more drastic procedures are undertaken.
使用间歇性血流血细胞分离机对镰状细胞病继发的阴茎异常勃起进行次全红细胞置换单采术，症状迅速缓解。该血细胞分离机为成人进行换血治疗提供了一种高效、实用且安全的方法。治疗阴茎异常勃起的外科手术成功率有限，且后续阳痿发生率为50%。我们认为，红细胞置换单采术为治疗镰状细胞危象的并发症（包括阴茎异常勃起）提供了一种更好的方法，对于有症状的患者，应在采取更激进的手术之前采用该方法。
