McLean D M, Chatiyanonda K, Ladyman S R, Brownlee J E
Can Med Assoc J. 1970 Jun 6;102(12):1247-51.
Enteroviruses were isolated from 11 of 1391 rectal swabs collected from 1103 infants aged less than 2 years who were hospitalized in Toronto, Ontario, and New Westminster, British Columbia, between April 1966 and March 1969. Viruses were recovered from 23 of 1231 rectal swabs obtained from 1076 age-matched control patients without gastroenteritis. The dominance of coxsackievirus and echovirus strains in Toronto patients with and without gastroenteritis contrasted sharply to their extremely low incidence in New Westminster where the Sabin attenuated strains of poliovirus composed the majority of isolates from both categories of patient. Although enteropathogenic bacteria were identified in 36 cases of gastroenteritis and 11 control subjects, no patient excreted a bacterial pathogen and a virus simultaneously.
1966年4月至1969年3月期间,从安大略省多伦多市和不列颠哥伦比亚省新威斯敏斯特市1103名2岁以下住院婴儿的1391份直肠拭子中,分离出了肠道病毒,共11份。从1076名无肠胃炎的年龄匹配对照患者的1231份直肠拭子中,分离出了23份病毒。在多伦多有肠胃炎和无肠胃炎的患者中,柯萨奇病毒和埃可病毒株占主导地位,这与新威斯敏斯特市极低的发病率形成鲜明对比,在新威斯敏斯特市,两类患者中分离出的病毒大多数是脊髓灰质炎病毒的萨宾减毒株。虽然在36例肠胃炎患者和11名对照受试者中鉴定出了肠道致病菌,但没有患者同时排出细菌病原体和病毒。