Grigor'ev A I, Korol'kov V I, Kozyrevskaia G I, Dotsenko M A
Kosm Biol Aviakosm Med. 1979 Sep-Oct;13(5):10-4.
It was demonstrated that a prolonged (24 days) bed rest at altitudes of 2200 m and 3200 m as well as at sea level was accompanied by an increased renal excretion of fluids and osmotically active substances, including electrolytes. Exercises done during bed rest indiced a smaller increase of the renal excretion of sodium and potassium. However, as bed rest continued the differences between the groups of test subjects disappeared. The levels of hypoxia and exercises used in the study proved inefficient to prevent changes in the fluid-electrolyte metabolism occurring during bed rest.
结果表明，在海拔2200米、3200米以及海平面进行为期24天的长期卧床休息，会导致包括电解质在内的液体和渗透活性物质的肾脏排泄增加。卧床休息期间进行的运动使钠和钾的肾脏排泄增加幅度较小。然而，随着卧床休息的持续，受试组之间的差异消失了。研究中使用的低氧水平和运动被证明无法有效防止卧床休息期间发生的液体电解质代谢变化。
