Byles A B, D'sa A
Br Med J. 1970 Sep 12;3(5723):625-7. doi: 10.1136/bmj.3.5723.625.
The use of promethazine and chloroquine sulphate to reduce reaction to total dose infusion of iron dextran (Imferon) is described. The patients chosen for the investigation were anaemic pregnant African women living in the coastal region of East Africa where malaria due to Plasmodium falciparum is holoendemic. The results show that promethazine has little value in the reduction of reactions whereas chloroquine appears to be effective.
描述了使用异丙嗪和硫酸氯喹来减轻对右旋糖酐铁(Imferon)全剂量输注的反应。被选入该研究的患者是居住在东非沿海地区的贫血非洲孕妇,该地区恶性疟原虫引起的疟疾呈高度地方性流行。结果表明,异丙嗪在减轻反应方面价值不大,而氯喹似乎有效。