癫痫的叶酸缺乏患者中的叶酸
Folic acid in folate-deficient patients with epilepsy.
作者信息
Grant R H, Stores O P
出版信息
Br Med J. 1970 Dec 12;4(5736):644-8. doi: 10.1136/bmj.4.5736.644.
Abstract
A double-blind trial using folic acid 15 mg. daily and identical placebo was carried out in 51 epileptic patients having a serum folate level below 3.6 ng./ml. Treatment was for a minimum of six months and in 41 patients was for more than one year. There were no significant changes in the frequency of seizures, behaviour, and personality, or in a number of cognitive functions.
摘要
对51名血清叶酸水平低于3.6纳克/毫升的癫痫患者进行了一项双盲试验，患者每日服用15毫克叶酸及外观相同的安慰剂。治疗期至少为六个月，41名患者的治疗期超过一年。癫痫发作频率、行为、性格以及一些认知功能均无显著变化。
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