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恶性贫血免疫现象的相关性研究。

A correlative study of immunological phenomena in pernicious anaemia.

作者信息

Strickland R G, Baur S, Ashworth L A, Taylor K B

出版信息

Clin Exp Immunol. 1971 Jan;8(1):25-36.

Abstract

Twenty patients with established pernicious anaemia have been studied by immunological techniques, in order to determine patterns of gastric antibody production. The presence of such antibodies and the immunoglobulin species in which they occur have been determined in serum, gastric juice and mononuclear inflammatory cells of the gastric mucosa. The lack of correlation found suggests that gastric antibodies in the gastric juice are not derived from serum and that serum and gastric juice antibodies are produced, regardless of immunoglobulin class, in some degree or wholly from different sites.

摘要

为了确定胃抗体产生的模式,我们运用免疫技术对20例确诊的恶性贫血患者进行了研究。已在血清、胃液以及胃黏膜的单核炎性细胞中测定了此类抗体的存在情况及其所出现的免疫球蛋白种类。所发现的缺乏相关性表明,胃液中的胃抗体并非源自血清,并且血清和胃液抗体,无论免疫球蛋白类别如何,在某种程度上或完全是由不同部位产生的。

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引用本文的文献

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Intestinal immunoglobulins in pernicious anemia.恶性贫血中的肠道免疫球蛋白。
Am J Dig Dis. 1974 Jul;19(7):623-5. doi: 10.1007/BF01073017.
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Gastritis.
Springer Semin Immunopathol. 1990;12(2-3):203-17. doi: 10.1007/BF00197506.

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