Juel-Jensen B E, MacCallum F O, Mackenzie A M, Pike M C
Br Med J. 1970 Dec 26;4(5738):776-80. doi: 10.1136/bmj.4.5738.776.
The antiviral effect of 5% idoxuridine in dimethyl sulphoxide intermittently applied and of 40% idoxuridine in dimethyl sulphoxide continuously applied for four days to the lesions in patients with zoster of recent onset was studied in two double-blind controlled trials. Most, but not all, of the patients receiving intermittent active treatment had pain for a short period only. The effect of continuous treatment was striking: pain had disappeared within nine days in all the patients and healing was accelerated. The results were statistically significant.
在两项双盲对照试验中,研究了将5%碘苷溶于二甲基亚砜中间歇应用以及将40%碘苷溶于二甲基亚砜连续应用四天对近期发病的带状疱疹患者皮损的抗病毒效果。大多数(但并非全部)接受间歇性积极治疗的患者仅在短时间内有疼痛。连续治疗的效果显著:所有患者的疼痛在九天内消失,愈合加速。结果具有统计学意义。