• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

用二甲亚砜中的碘苷治疗带状疱疹。两项双盲对照试验的结果。

Treatment of zoster with idoxuridine in dimethyl sulphoxide. Results of two double-blind controlled trials.

作者信息

Juel-Jensen B E, MacCallum F O, Mackenzie A M, Pike M C

出版信息

Br Med J. 1970 Dec 26;4(5738):776-80. doi: 10.1136/bmj.4.5738.776.

DOI:10.1136/bmj.4.5738.776
PMID:4925077
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1820395/
Abstract

The antiviral effect of 5% idoxuridine in dimethyl sulphoxide intermittently applied and of 40% idoxuridine in dimethyl sulphoxide continuously applied for four days to the lesions in patients with zoster of recent onset was studied in two double-blind controlled trials. Most, but not all, of the patients receiving intermittent active treatment had pain for a short period only. The effect of continuous treatment was striking: pain had disappeared within nine days in all the patients and healing was accelerated. The results were statistically significant.

摘要

在两项双盲对照试验中,研究了将5%碘苷溶于二甲基亚砜中间歇应用以及将40%碘苷溶于二甲基亚砜连续应用四天对近期发病的带状疱疹患者皮损的抗病毒效果。大多数(但并非全部)接受间歇性积极治疗的患者仅在短时间内有疼痛。连续治疗的效果显著:所有患者的疼痛在九天内消失,愈合加速。结果具有统计学意义。

相似文献

1
Treatment of zoster with idoxuridine in dimethyl sulphoxide. Results of two double-blind controlled trials.用二甲亚砜中的碘苷治疗带状疱疹。两项双盲对照试验的结果。
Br Med J. 1970 Dec 26;4(5738):776-80. doi: 10.1136/bmj.4.5738.776.
2
Idoxuridine in herpes zoster: further evaluation of intermittent topical therapy.疱疹净治疗带状疱疹:间歇性局部治疗的进一步评估
Br Med J. 1974 Jun 8;2(5918):526-7. doi: 10.1136/bmj.2.5918.526.
3
Idoxuridine in the treatment of herpes zoster.
Practitioner. 1975 Aug;215(1286):226-9.
4
A multicentre trial of Zostrum (5 percent idoxuridine in dimethyl sulphoxide) in herpes zoster.
N Z Med J. 1981 Nov 25;94(696):384-6.
5
Treatment of herpes zoster with idoxuridine ointment, including a multivariate analysis of symptoms and signs.
Scand J Infect Dis. 1979;11(1):1-9. doi: 10.3109/inf.1979.11.issue-1.01.
6
Letter: Idoxuridine in herpes zoster.信函:疱疹性带状疱疹中的碘苷。
Br Med J. 1974 Aug 24;3(5929):523. doi: 10.1136/bmj.3.5929.523-a.
7
The use of betadine antiseptic paint in the treatment of Herpes simplex and Herpes Zoster.
J Int Med Res. 1977;5(5):378-81. doi: 10.1177/030006057700500516.
8
Treatment of trigeminal and thoracic zoster with idoxuridine.
Scand J Infect Dis. 1981;13(4):257-62. doi: 10.3109/inf.1981.13.issue-4.03.
9
[Results of a field study using idoxuridine in dimethylsulfoxide in the treatment of herpes zoster and herpes simplex].[使用二甲基亚砜中的碘苷治疗带状疱疹和单纯疱疹的现场研究结果]
Z Hautkr. 1980 Jun 15;55(12):773-81.
10
Herpes simplex virus skin infection in man treated with idoxuridine in dimethyl sulphoxide. Results of double-blind controlled trial.用二甲亚砜中的碘苷治疗人类单纯疱疹病毒皮肤感染。双盲对照试验结果。
Br Med J. 1966 Oct 1;2(5517):805-7. doi: 10.1136/bmj.2.5517.805.

引用本文的文献

1
The cancer patient with chronic pain due to herpes zoster.患有带状疱疹所致慢性疼痛的癌症患者。
Curr Rev Pain. 2000;4(6):429-36. doi: 10.1007/s11916-000-0066-7.
2
Herpes zoster and postherpetic neuralgia. Optimal treatment.带状疱疹及带状疱疹后神经痛。最佳治疗方法。
Drugs Aging. 1997 Feb;10(2):80-94. doi: 10.2165/00002512-199710020-00002.
3
Antiviral therapy of acute herpes zoster in older patients.老年患者急性带状疱疹的抗病毒治疗
Drugs Aging. 1996 Feb;8(2):97-112. doi: 10.2165/00002512-199608020-00004.
4
Primary care management of acute herpes zoster: systematic review of evidence from randomized controlled trials.急性带状疱疹的初级保健管理:来自随机对照试验证据的系统评价
Br J Gen Pract. 1995 Jan;45(390):39-45.
5
The effect of dimethyl sulfoxide on tissue distribution of gentamicin.
Experientia. 1980 Jan 15;36(1):92-3. doi: 10.1007/BF02003993.
6
Topical acyclovir in herpes zoster ocular involvement.局部用阿昔洛韦治疗眼部带状疱疹
Br J Ophthalmol. 1981 Aug;65(8):542-5. doi: 10.1136/bjo.65.8.542.
7
Idoxuridine in Herpes Zoster.疱疹净治疗带状疱疹
Br Med J. 1974 Jul 6;3(5922):41.
8
Idoxuridine in herpes zoster: further evaluation of intermittent topical therapy.疱疹净治疗带状疱疹:间歇性局部治疗的进一步评估
Br Med J. 1974 Jun 8;2(5918):526-7. doi: 10.1136/bmj.2.5918.526.
9
Antiviral chemotherapy: the first decade.抗病毒化疗:头十年
Br Med J. 1973 Aug 4;3(5874):275-9. doi: 10.1136/bmj.3.5874.275.
10
Herpes simplex and zoster.单纯疱疹和带状疱疹。
Br Med J. 1973 Feb 17;1(5850):406-10. doi: 10.1136/bmj.1.5850.406.

本文引用的文献

1
TREATMENT OF HERPES ZOSTER WITH HIGH DOSES OF PREDNISONE.大剂量泼尼松治疗带状疱疹
Lancet. 1964 Sep 19;2(7360):610-1. doi: 10.1016/s0140-6736(64)90507-0.
2
SPREAD OF ZOSTER VIRUS IN HUMAN EMBRYONIC LUNG CELLS AND THE INHIBITORY EFFECT OF LODODEOXYURIDINE.带状疱疹病毒在人胚肺细胞中的传播及碘脱氧尿苷的抑制作用
Virology. 1964 Mar;22:321-30. doi: 10.1016/0042-6822(64)90023-6.
3
DISSEMINATED HERPES ZOSTER. A REPORT OF 17 CASES.播散性带状疱疹。17例报告。
Arch Intern Med. 1964 May;113:679-86. doi: 10.1001/archinte.1964.00280110059012.
4
Ranking procedures for arbitrarily restricted observation.任意受限观察的排序程序。
Biometrics. 1967 Mar;23(1):65-78.
5
Severe generalized primary herpes treated with cytarabine.用阿糖胞苷治疗的严重全身性原发性疱疹。
Br Med J. 1970 Apr 18;2(5702):154-5. doi: 10.1136/bmj.2.5702.154.
6
Herpes simplex virus skin infection in man treated with idoxuridine in dimethyl sulphoxide. Results of double-blind controlled trial.用二甲亚砜中的碘苷治疗人类单纯疱疹病毒皮肤感染。双盲对照试验结果。
Br Med J. 1966 Oct 1;2(5517):805-7. doi: 10.1136/bmj.2.5517.805.
7
The effects of early corticosteroid therapy on the skin eruption and pain of herpes zoster.早期皮质类固醇疗法对带状疱疹皮肤疹和疼痛的影响。
JAMA. 1970 Mar 9;211(10):1681-3.
8
Herpetic whitlows: results of treatment with idoxuridine.
J Am Coll Health Assoc. 1970 Feb;18(3):227-30.
9
Clinical studies with systemic administration of antimetabolites of pyrimidine nucleosides in viral infections.
Ann N Y Acad Sci. 1965 Jul 30;130(1):192-208. doi: 10.1111/j.1749-6632.1965.tb12552.x.