YNDESTAD M, LOFTSGåRD G
Acta Vet Scand. 1970;11(4):594-9. doi: 10.1186/BF03547958.
Investigations to determine the exact susceptibility of mink to Clostridium botulinum type C toxin clearly showed that mink were considerably less resistant to this toxin than has previously been described. Mink weighing approximately 900 g were killed by 360 MLD when toxin was mixed into the feed. By subcutaneous injection, the lethal dose was determined to be in the range of 18 to 36 MLD. When comparing the susceptibility per g of body weight after parenteral application of the toxin, mink proved to be less resistant than mice to this type of toxin. Continued feeding tests in mink with suspected material is pointed out as a preferable method for practical demonstrations of Clostridium botulinum type C toxin in cases where the toxin content in the suspected material is very low (1 MLD per g or less).
旨在确定水貂对C型肉毒梭菌毒素确切易感性的调查清楚地表明，水貂对这种毒素的抵抗力比之前描述的要低得多。当将毒素混入饲料中时，体重约900克的水貂被360个最小致死量杀死。通过皮下注射，致死剂量确定在18至36个最小致死量范围内。在经肠胃外应用毒素后比较每克体重的易感性时，水貂被证明对这种毒素的抵抗力比小鼠低。在疑似材料中，毒素含量非常低（每克1个最小致死量或更低）的情况下，指出对水貂进行持续的喂食测试是实际检测C型肉毒梭菌毒素的一种较好方法。
