Debas H T, Cohen M M, Holubitsky I B, Harrison R C
Gut. 1971 Feb;12(2):93-6. doi: 10.1136/gut.12.2.93.
The effect of smoking three cigarettes over a one-hour period on the pentagastrinstimulated submaximal plateau of acid and pepsin secretion was observed in 12 healthy human volunteers comprising men and women and smokers and non-smokers. No significant overall change in secretion was observed. In one subject, however, acid secretion was significantly inhibited (p < 0.01) and in one individual significant late stimulation (p < 0.01) of both acid and pepsin was observed.
在12名包括男性和女性、吸烟者和非吸烟者的健康人类志愿者中,观察了在一小时内吸三支烟对五肽胃泌素刺激的次最大胃酸和胃蛋白酶分泌平台期的影响。未观察到分泌有显著的总体变化。然而,在一名受试者中,胃酸分泌受到显著抑制(p<0.01),在一名个体中,观察到胃酸和胃蛋白酶均有显著的后期刺激(p<0.01)。