A temperature-sensitive thy mutant blocked in the synthesis of thymidylate synthetase.

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作者信息

Roodman S T, Greenberg G R

出版信息

J Biol Chem. 1971 Apr 25;246(8):2609-17.

PMID:4928648

Abstract

摘要

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A temperature-sensitive thy mutant blocked in the synthesis of thymidylate synthetase.

J Biol Chem. 1971 Apr 25;246(8):2609-17.

Conditions allowing synthesis of thymidylate synthetase at the nonpermissive temperature in a temperature-sensitive thy mutant normally blocked in its translation.在温度敏感型thy突变体中，允许在非许可温度下合成胸苷酸合成酶的条件，该突变体通常在其翻译过程中受阻。

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