大肠杆菌K-12的胸腺嘧啶核苷需求型突变体的抑制作用。
Suppression by thymidine-requiring mutants of Escherichia coli K-12.
作者信息
Herrington M B, Kohli A, Lapchak P H
出版信息
J Bacteriol. 1984 Jan;157(1):126-9. doi: 10.1128/jb.157.1.126-129.1984.
Abstract
Thymidine-requiring strains of Escherichia coli isolated by trimethoprim selection often simultaneously acquire the ability to suppress bacteriophage T4 nonsense mutations. Suppression is lost in Thy+ revertants and recombinants, but is sometimes retained in thyA plasmid-bearing transformants. Suppression is restricted in Strr derivatives of the Thy- mutants, indicating that suppression occurs at the level of translation.
摘要
通过甲氧苄啶筛选分离出的大肠杆菌胸腺嘧啶核苷需求菌株常常同时获得抑制噬菌体T4无义突变的能力。在Thy+回复体和重组体中抑制作用消失，但在携带thyA质粒的转化体中有时会保留。抑制作用在Thy-突变体的Strr衍生物中受到限制，这表明抑制作用发生在翻译水平。
相似文献
1
Suppression by thymidine-requiring mutants of Escherichia coli K-12.大肠杆菌K-12的胸腺嘧啶核苷需求型突变体的抑制作用。
J Bacteriol. 1984 Jan;157(1):126-9. doi: 10.1128/jb.157.1.126-129.1984.
2
Frameshift suppression by thyA mutants of Escherichia coli K-12.大肠杆菌K-12的thyA突变体的移码抑制作用
Genetics. 1986 Nov;114(3):705-16. doi: 10.1093/genetics/114.3.705.
3
Nonsense suppression in thymine-requiring strains of Escherichia coli is a consequence of altered folate metabolism.在需要胸腺嘧啶的大肠杆菌菌株中，无义抑制是叶酸代谢改变的结果。
Mol Gen Genet. 1993 Apr;238(1-2):218-24. doi: 10.1007/BF00279550.
4
Kasugamycin inhibition of nonsense suppression by thymine-requiring strains of Escherichia coli K12.春日霉素对大肠杆菌K12胸腺嘧啶需求菌株无义抑制的抑制作用。
Can J Microbiol. 1993 Apr;39(4):448-50. doi: 10.1139/m93-065.
5
Trimethoprim-produced F-specific insertion mutations in Escherichia coli K-12.甲氧苄啶诱导大肠杆菌K-12中F特异性插入突变。
J Bacteriol. 1982 May;150(2):755-61. doi: 10.1128/jb.150.2.755-761.1982.
6
The isolation of thymidine-requiring Haemophilus influenzae from the sputum of chronic bronchitic patients receiving trimethoprim.从接受甲氧苄啶治疗的慢性支气管炎患者痰液中分离出需要胸苷的流感嗜血杆菌。
J Antimicrob Chemother. 1983 Mar;11(3):281-6. doi: 10.1093/jac/11.3.281.
7
8
Suppression of recJ mutations of Escherichia coli by mutations in translation initiation factor IF3.通过翻译起始因子IF3中的突变抑制大肠杆菌recJ突变
J Bacteriol. 1993 Oct;175(19):6118-25. doi: 10.1128/jb.175.19.6118-6125.1993.
9
10
Thermoresistant revertants of an Escherichia coli strain carrying tif-1 and ruv mutations: non-suppressibility of ruv by sfi.携带tif-1和ruv突变的大肠杆菌菌株的耐热回复突变体：sfi对ruv的不可抑制性
J Bacteriol. 1979 Apr;138(1):1-6. doi: 10.1128/jb.138.1.1-6.1979.
引用本文的文献
1
Linkage map of Escherichia coli K-12, edition 10: the traditional map.大肠杆菌K-12连锁图谱，第10版：传统图谱。
Microbiol Mol Biol Rev. 1998 Sep;62(3):814-984. doi: 10.1128/MMBR.62.3.814-984.1998.
2
Nonsense suppression in thymine-requiring strains of Escherichia coli is a consequence of altered folate metabolism.在需要胸腺嘧啶的大肠杆菌菌株中，无义抑制是叶酸代谢改变的结果。
Mol Gen Genet. 1993 Apr;238(1-2):218-24. doi: 10.1007/BF00279550.
3
Frameshift suppression by thyA mutants of Escherichia coli K-12.大肠杆菌K-12的thyA突变体的移码抑制作用
Genetics. 1986 Nov;114(3):705-16. doi: 10.1093/genetics/114.3.705.
本文引用的文献
1
Characterization of mutants of Escherichia coli with an increased control of translation fidelity.对翻译保真度控制增强的大肠杆菌突变体的表征。
Mol Gen Genet. 1983;189(1):123-8. doi: 10.1007/BF00326064.
2
Characterization of the Escherichia coli thyA gene and its amplified thymidylate synthetase product.大肠杆菌thyA基因及其扩增的胸苷酸合成酶产物的特性分析。
Proc Natl Acad Sci U S A. 1983 Apr;80(7):1858-61. doi: 10.1073/pnas.80.7.1858.
3
Suppression by an Escherichia coli mutant under thymine-limiting conditions.大肠杆菌突变体在胸腺嘧啶限制条件下的抑制作用。
Mutat Res. 1983 Feb;119(2):109-11. doi: 10.1016/0165-7992(83)90118-5.
4
Thymine inhibits suppression by an Escherichia coli nonsense and frameshift suppressor.
Mol Gen Genet. 1982;186(2):217-20. doi: 10.1007/BF00331852.
5
6
Altered ribosomes in a suppressor strain of Escherichia coli.大肠杆菌抑制菌株中核糖体的改变。
J Mol Biol. 1966 Apr;16(2):285-301. doi: 10.1016/s0022-2836(66)80173-0.
7
Isolation and characterization of ribonuclease I mutants of Escherichia coli.大肠杆菌核糖核酸酶I突变体的分离与鉴定
J Mol Biol. 1966 Mar;16(1):67-84. doi: 10.1016/s0022-2836(66)80263-2.
8
A genetical study of thymineless mutants of E. coli K12.
Genet Res. 1966 Aug;8(1):83-100. doi: 10.1017/s0016672300009939.
9
Thymidylate synthesis and aminopterin resistance in Bacillus subtilis.枯草芽孢杆菌中的胸苷酸合成与氨甲蝶呤抗性
J Bacteriol. 1966 Jul;92(1):186-96. doi: 10.1128/jb.92.1.186-196.1966.
10
A temperature-sensitive thy mutant blocked in the synthesis of thymidylate synthetase.
J Biol Chem. 1971 Apr 25;246(8):2609-17.
Zotero 插件