Fahnestock S, Rich A
Science. 1971 Jul 23;173(3994):340-3. doi: 10.1126/science.173.3994.340.
Deamination of phenylalanyl-transfer RNA with nitrous acid yields the alpha-hydroxyacyl analog, phenyllactyl-transfer RNA. When this is incubated in a protein-synthesizing system directed by polyuridylic acid, it yields an acid-precipitable, alkali-labile polyester of phenyllactic acid.
用亚硝酸对苯丙氨酰 - 转移核糖核酸进行脱氨基作用会产生α - 羟基酰基类似物,即苯乳酸基 - 转移核糖核酸。当将其在由聚尿苷酸指导的蛋白质合成系统中孵育时,会产生一种酸可沉淀、碱不稳定的苯乳酸聚酯。