Suoranta H, Standertskjöld-Nordenstam C G, Lähde S
Radiology. 1979 Nov;133(2):307-8. doi: 10.1148/133.2.307.
The effectiveness of simethicone in reducing the amount of gastrointestinal gas was investigated with abdominal radiographs in a double-blind study of 169 patients receiving either simethicone or a placebo randomly. There was no statistically significant difference between the two groups. Although simethicone may relieve clinical symptoms and accelerate the transit time of gas, it does not reduce the amount of gas in the gastrointestinal tract. This study indicates that simethicone is not helpful in preparing the patient for radiological examination of the abdomen.
在一项针对169名随机接受西甲硅油或安慰剂治疗的患者的双盲研究中，通过腹部X光片对西甲硅油减少胃肠道气体量的有效性进行了调查。两组之间没有统计学上的显著差异。尽管西甲硅油可能会缓解临床症状并加快气体通过时间，但它并不能减少胃肠道内的气体量。这项研究表明，西甲硅油对患者进行腹部放射学检查的准备并无帮助。
