肌肉注射2和10剂量的利多卡因
Intramuscular lignocaine 2 and 10 .
作者信息
Jebson P
出版信息
Br Med J. 1971 Sep 4;3(5774):566-7. doi: 10.1136/bmj.3.5774.566.
Abstract
Studies in 10 male volunteers has shown that intramuscular injection of 10% lignocaine produces similar blood lignocaine levels to those obtained with larger volumes of a less concentrated preparation. Since no local or general complications occurred it is suggested that the 10% solution is suitable for clinical use.
摘要
对10名男性志愿者的研究表明，肌肉注射10%的利多卡因所产生的血液利多卡因水平，与使用更大剂量、浓度较低的制剂所获得的水平相似。由于未发生局部或全身并发症，因此建议10%的溶液适用于临床使用。
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本文引用的文献
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THE SYSTEMIC ABSORPTION OF LOCAL ANALGESIC DRUGS.局部麻醉药的全身吸收
Br J Anaesth. 1965 Jun;37:394-404. doi: 10.1093/bja/37.6.394.
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The determination of lidocaine and prilocaine in whole blood by gas chromatography.气相色谱法测定全血中的利多卡因和丙胺卡因
Anesthesiology. 1968 Jan-Feb;29(1):110-2. doi: 10.1097/00000542-196801000-00029.
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Plasma-levels of lignocaine after intramuscular injection.肌肉注射后利多卡因的血浆水平。
Lancet. 1968 Dec 7;2(7580):1209-10. doi: 10.1016/s0140-6736(68)91692-9.
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