Viallat J R, Boutin C, Gbiorczyk R
Rev Fr Mal Respir. 1979 May-Jun;7(3):305-10.
The skin response to 1 microgram Phytohemagglutinin (PHA) was studied in 359 subject including 235 cancer patients and 124 without cancer. Responses to PHA, tuberculin, candidin were compared. A positive skin response to PHA was observed in 88% of patients without malignancy. This percentage remained almost equal in older patients (more than 70 years). Among patients with advanced malignancies, there was a fall down to 64.5% of the percentage of positive responses. A negative response to both PHA and tuberculin was observed in 6% of patients without malignancy and 28% of cancer patients. 38 +/- 5 days was the average survival of this last group. The arguments favouring the fact that PHA induces cutaneous basophilic hypersensitivity are reviewed. An advantage of this test is that no presensitization is required.
在359名受试者中研究了皮肤对1微克植物血凝素（PHA）的反应，其中包括235名癌症患者和124名非癌症患者。比较了对PHA、结核菌素、念珠菌素的反应。在88%的非恶性肿瘤患者中观察到对PHA的阳性皮肤反应。在老年患者（70岁以上）中，这一百分比几乎保持不变。在晚期恶性肿瘤患者中，阳性反应百分比降至64.5%。在6%的非恶性肿瘤患者和28%的癌症患者中观察到对PHA和结核菌素均呈阴性反应。最后一组患者的平均生存期为38±5天。回顾了支持PHA诱导皮肤嗜碱性超敏反应这一事实的论据。该试验的一个优点是不需要预先致敏。
