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用植物血凝素进行皮内试验以检测细胞介导的免疫反应(作者译)

[Intracutaneous tests with phytohemagglutinin for detection of cell-mediated immunity (author's transl)].

作者信息

Westphal H J, Kaben U

出版信息

Allerg Immunol (Leipz). 1979;25(4):275-80.

PMID:161949
Abstract

Patients with various forms of dermatosis and healthy control subjects were simultaneously tested intracutaneously with specific antigens (candidin, trichophytin, kabikinase, tuberculin and the mumps skin test antigen) and the non-specificmitogen PHA-P. A positive delayed reaction was observed in 98% of the healthy subjects and 76,6% of the dermatosis patients following intracutaneous application of 2 microgram PHA-P.--The results of these studies suggest that the PHA-P intracutaneous test might be suitable as a screening method for diagnozing cellular immun-defects.

摘要

对患有各种皮肤病的患者和健康对照者同时进行皮内注射特定抗原(白色念珠菌素、发癣菌素、卡比激酶、结核菌素和腮腺炎皮肤试验抗原)以及非特异性有丝分裂原PHA-P的检测。皮内注射2微克PHA-P后,98%的健康受试者和76.6%的皮肤病患者出现了阳性迟发型反应。——这些研究结果表明,PHA-P皮内试验可能适合作为诊断细胞免疫缺陷的一种筛查方法。

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