Shibasaki H, Kato M
J Neurol. 1975;208(3):191-9. doi: 10.1007/BF00630632.
Cortical potentials associated with unilateral and bilateral simultaneous thumb opposition were studied in 9 healthy subjects. The P1 component, "pre-motion positivity", was recognized in 5 out of 9 subjects on unilateral thumb movement. In all subjects in whom P1 was recognized, P1 was dominant over the cerebral hemisphere ipsilateral to the contracting muscles. On bilateral simultaneous thumb movement, however, P1 was not discerned in any subject. This is compatible with the assumption that P1 is related to an inhibition of imitative movement of the opposite hand (mirror movement). The N2 component had its onset after the start of muscle contraction in most cases, suggesting that N2 might not reflect activation of the corticospinal pathways.
对9名健康受试者进行了与单侧和双侧同时拇指对掌相关的皮质电位研究。在9名单侧拇指运动的受试者中，有5名识别出了P1成分，即“运动前正波”。在所有识别出P1的受试者中，P1在收缩肌肉同侧的大脑半球占主导地位。然而，在双侧同时拇指运动时，没有任何受试者能识别出P1。这与P1与对侧手模仿运动（镜像运动）抑制有关的假设相符。在大多数情况下，N2成分在肌肉收缩开始后出现，这表明N2可能不反映皮质脊髓通路的激活。
