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麻风分枝杆菌表面的肽糖脂细丝。

Surface peptido-glycolipid filaments on Mycobacterium leprae.

作者信息

Gordon J, White R G

出版信息

Clin Exp Immunol. 1971 Oct;9(4):539-47.

PMID:4941663
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1713009/
Abstract

was shown to possess a superficial network of filaments fundamentally identical with the adjuvant active peptido-glycolipid filaments present on all other mycobacteria, and in biologically active wax D derived from and related organisms. Differences between the filaments seen on recovered from human lepromatous tissue and those demonstrated on mycobacteria grown in artificial culture are attributed to the effect of prolonged intracellular existence in a host phagocyte and are given as evidence of sensitivity of peptido-glycolipid to the action of intracellular enzymes.

摘要

结果表明,它具有一个表面丝状网络,与所有其他分枝杆菌上存在的佐剂活性肽糖脂丝以及从相关生物体衍生的具有生物活性的蜡D中的丝状网络基本相同。从人类麻风组织中分离出的[具体分枝杆菌名称未给出]上观察到的丝与在人工培养中生长的分枝杆菌上显示的丝之间的差异,归因于在宿主吞噬细胞中长时间细胞内存活的影响,并作为肽糖脂对细胞内酶作用敏感性的证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e673/1713009/ca24758c5db7/clinexpimmunol00371-0108-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e673/1713009/866350c2ae4f/clinexpimmunol00371-0103-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e673/1713009/5e0196338042/clinexpimmunol00371-0105-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e673/1713009/a4d58f2dbde8/clinexpimmunol00371-0107-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e673/1713009/ca24758c5db7/clinexpimmunol00371-0108-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e673/1713009/866350c2ae4f/clinexpimmunol00371-0103-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e673/1713009/5e0196338042/clinexpimmunol00371-0105-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e673/1713009/a4d58f2dbde8/clinexpimmunol00371-0107-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e673/1713009/ca24758c5db7/clinexpimmunol00371-0108-a.jpg

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1
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引用本文的文献

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Infect Immun. 1972 Dec;6(6):909-12. doi: 10.1128/iai.6.6.909-912.1972.
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The problem of cultivation of Mycobacterium leprae. A review with criteria for evaluating recent experimental work.麻风分枝杆菌的培养问题。对近期实验工作评估标准的综述。

本文引用的文献

1
Chemical factors involved in the induction of infectious allergy.诱导感染性过敏所涉及的化学因素。
Experientia. 1950 Nov 15;6(11):410-9. doi: 10.1007/BF02150118.
2
CORRELATION OF ADJUVANT ACTIVITY AND CHEMICAL STRUCTURE OF WAX D FRACTIONS OF MYCOBACTERIA.分枝杆菌蜡质D组分的佐剂活性与化学结构的相关性
Immunology. 1964 Mar;7(2):158-71.
3
Growth of Mycobacterium lepraemurium maintained in cultures of rat fibrolasts.维持在大鼠成纤维细胞培养物中的鼠麻风分枝杆菌的生长。
Bull World Health Organ. 1973;49(4):403-10.
4
Cytochemical reactions of human leprosy bacilli and mycobacteria: ultrastructural implications.人类麻风杆菌和分枝杆菌的细胞化学反应:超微结构方面的意义
J Bacteriol. 1973 Mar;113(3):1389-99. doi: 10.1128/jb.113.3.1389-1399.1973.
5
A lipid chemotactic factor from anaerobic coryneform bacteria including Corynebacterium parvum with activity for macrophages and monocytes.一种来自厌氧棒状杆菌(包括短小棒状杆菌)的脂质趋化因子,对巨噬细胞和单核细胞具有活性。
Immunology. 1976 Jun;30(6):935-49.
6
Comparative ultrastructure of Mycobacterium leprae and Mycobacterium lepraemurium cell envelopes.麻风分枝杆菌和鼠麻风分枝杆菌细胞壁的比较超微结构
J Bacteriol. 1979 May;138(2):552-8. doi: 10.1128/jb.138.2.552-558.1979.
7
Mycobacterium.分枝杆菌属
Bacteriol Rev. 1977 Mar;41(1):217-372. doi: 10.1128/br.41.1.217-372.1977.
J Gen Microbiol. 1962 Feb;27:259-68. doi: 10.1099/00221287-27-2-259.
4
A negative staining method for high resolution electron microscopy of viruses.一种用于病毒高分辨率电子显微镜观察的负染色方法。
Biochim Biophys Acta. 1959 Jul;34:103-10. doi: 10.1016/0006-3002(59)90237-9.
5
The role of various chemical fractions of M. tuberculosis and other Mycobacteria in the production of allergic encephalomyelitis.结核分枝杆菌及其他分枝杆菌的各种化学成分在变应性脑脊髓炎产生中的作用。
Immunology. 1958 Apr;1(2):111-22.
6
Role of adjuvants in the production of delayed hypersensitivity.佐剂在迟发型超敏反应产生中的作用。
Br Med Bull. 1967 Jan;23(1):39-45. doi: 10.1093/oxfordjournals.bmb.a070514.
7
Mycobacteria and lysosomes: a paradox.分枝杆菌与溶酶体:一个悖论。
Nature. 1969 Feb 15;221(5181):658-60. doi: 10.1038/221658a0.
8
Cellular hypersensitivity and cellular immunity in the pathogensis of tuberculosis: specificity, systemic and local nature, and associated macrophage enzymes.细胞超敏反应和细胞免疫在结核病发病机制中的作用:特异性、全身性和局部性以及相关巨噬细胞酶
Bacteriol Rev. 1968 Jun;32(2):85-102. doi: 10.1128/br.32.2.85-102.1968.